Estrogen Receptors And Cancer | What Is The Truth About Estrogen And Cancer? https://drthomaslodi.com/
Estrogen receptors and cancer, this is a big topic and a very confusing topic. So, what is the truth about estrogen and cancer? The politics in all of this is troubling. You can no longer do effective research to find out the truth on estrogen receptors and cancer.
For example, when searching on Google, you can search on the first 10 pages and all you will find is mainstream allopathic information. You won’t find doctors and scientists like me putting out the truth that is counter to the conventional model.
When we talk about estrogen receptors and cancer we are not talking about just breast, uterine, and ovarian because estrogen receptors and cancer include colon cancer, lung cancer, brain cancer, pancreatic cancer, prostate cancer, melanoma, and even some bone marrow and blood cancers.
There are two subtypes of estrogen receptors, alpha, and beta. The estrogen molecule binds to either the alpha or the beta. If it binds to the alpha, it has one set of effects and if it binds to the beta, it has another set of effects. Then we must look at which estrogens bind to alpha, and which bind to beta.
The effect is not the estrogen itself; it is the receptor it binds to and that is where the downstream effects occur. There are three main groups of estrogen, estrone, estradiol, and estriol also known as E1, E2, and E3.
What’s interesting about Estrone and Estradiol is that they are the same kind of effect on the alphas and the betas. However, they have a higher affinity for the alphas. Estriol has a higher affinity for the betas. The strongest and most powerful is the Estradiol. This is the main estrogen and the one they use when testing for cancer.
All the steroid hormones include sex hormones, testosterone, progesterone, estrogen, and cortisol. When a doctor says I’m going to put you on steroids, they are talking about synthetic derivatives of cortisol. All the steroid hormones are derived from cholesterol. Cholesterol changes into the parent hormone of all sex hormones and that are called pregnenolone.
The alpha receptors are mainly present in the breast, uterus, part of the ovary, the male reproductive organs, prostate, and liver. The estrogen receptor beta is present in the brain and the immune system.
Both the alpha and beta estrogen receptors are expressed significantly in the cardiovascular system and the central nervous system. This is important because of our cardiovascular health. When a woman goes through menopause it increases her risk for cardiovascular disease so much so that it has become the number one killer of older women. These deaths even surpass those of cancer. This is a result of the protective effect of estrogen.
The estrogen beta receptors function as a tumor suppressor with anti-proliferative actions. Conversely, the estrogen alpha receptors when stimulated cause tumor proliferation and growth. That is an enormous difference between the two of them. Alpha helps tumors grow and Beta shrinks them down.
There are different cancer types that produce extra estrogen receptor betas where the cancer is not aggressive and slow-growing. The estrogen receptor alphas are more prevalent in the mammary glands and uterus.
If a male is diagnosed with prostate cancer, activating Estrogen receptor beta can prevent the tumor from growing any further and actually shrink it.
It is so important to understand this was men dealing with this diagnosis. The description for a video only holds so many words and Dr. Lodi gives so much value in this lecture so we urge you to watch every minute as not all the data he gave can be recorded here. We hope you enjoyed this talk on estrogen receptors and cancer.
